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KMID : 0816120040070010087
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Korean Journal of Pediatric Gastroenterolology and Nutrition
2004 Volume.7 No. 1 p.87 ~ p.91
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Cytomegalovirus-induced Childhood Menetrier’s Disease with Peripheral Eosinophilia
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Choi Won-Joung
Lee Hee-Jung
Hwang Jin-Bok
Oh Hoon-Kyu
Lee Bo-Young
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Abstract
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Herein, the case of a 5-year-old boy with cytomegalovirus-induced Menetrier’s disease, with peripheral eosinophilia, presenting with abdominal pain and vomiting, followed by generalized edema, is reported. The initial laboratory findings, hypoalbuminemia and peripheral eosinophilia were noted, with no evidence of renal, hepatic, cardiac or allergic diseases. Gastrofiberscopy was performed under the suspicion of eosinophilic gastroenteritis with protein losing gastropathy. The gastrofiberscopy showed the characteristic features of giant hypertrophy of the gastric rugae, with large quantities of adherent gelatinous material on the gastric fundus and body. The histological findings revealed foveolar hyperplasia, compatible with Menetrier’s disease, with massive eosinophilic infiltrations. The presence of cytomegalovirus infection was identified by serology and confirmed by urine PCR. His symptoms, gastrofiberscopic findings and peripheral eosinophilia resolved spontaneously, and he has remained well for 10 months.
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KEYWORD
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Menetrier`s disease, Cytomegalovirus, Eosinophilia
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